A straightforward, environmentally benefcial synthesis of spiro[diindeno[1,2‑b:2′,1′‑e]py ridine‑11,3′‑indoline]‑2′,10,12‑tri ones mediated by a nano‑ordered reusable catalyst

Demchuk, Oleg M.Fathi, MahsaNaimi-Jamal, M. RezaDekamin, Mohammad G.Panahi, Leila2022-06-232022-06-232021"Scientifc Reports", 2021, Vol. 11, 4820http://hdl.handle.net/20.500.12153/3233A library of new spiro[diindeno[1,2-b:2′,1′-e]pyridine-11,3′-indoline]-2′,10,12-trione derivatives has been prepared in an efficient, one-pot pseudo four-component method mediated by a reusable heterogeneous nano-ordered mesoporous SO3H functionalized-silica (MCM-41-SO3H) catalyst. Excellent yields, short reaction times, as well as convenient non-chromatographic purification of the products and environmental benefits such as green and metal-free conditions constitute the main advantages of the developed synthetic methodology. The obtained fused indole-indenone dyes would be of interest to pharmaceutical and medicinal chemistry. Furthermore, due to their sensitivity to pH changes, they could be used as novel pH indicators.enUznanie autorstwa-Użycie niekomercyjne-Bez utworów zależnych 3.0 Polskahttp://creativecommons.org/licenses/by-nc-nd/3.0/pl/A straightforward, environmentally benefcial synthesis of spiro[diindeno[1,2‑b:2′,1′‑e]py ridine‑11,3′‑indoline]‑2′,10,12‑tri ones mediated by a nano‑ordered reusable catalystinfo:eu-repo/semantics/article10.1038/s41598-021-84209-6